Case Closed Season 1 Episode 496 Clash of Red and Black! (Invasion) ( Air Date 2008-02-18 ) Genre Animation, Crime, Mystery, Comedy category. Overview "The nurse tells Conan that she just remembered Eisuke had surgery for leukemia when he was young, raising the possibility Rena may in fact be his sister.".
Case Closed Season 1 Episode 496 Clash of Red and Black! (Invasion)
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- Watch: Case Closed Season 1 Episode 496 Clash of Red and Black! (Invasion) on CWR-CRB
- Stars: Minami Takayama, Kappei Yamaguchi, Wakana Yamazaki, Akira Kamiya, Rikiya Koyama, Megumi Hayashibara, Kenichi Ogata, Yukiko Iwai, Wataru Takagi, Ikue Otani, Chafurin
- Director: Gosho Aoyama
